Propranolol: Dosage, How to use, Side Effects

Propranolol: Dosage, How to use, Side Effects

What is Propranolol?

Propranolol is a beta-adrenergic blocking agent used to treat high blood pressure, heart pain (angina pectoris), abnormal heart rhythms, and some neurological diseases. Other examples of beta-adrenergic blockers include metoprolol (loopersor), atenolol (tenormin), and timolol (blochkaden).

Neurotransmitters are chemicals that are produced and distributed by the nerves to communicate. The released neurotransmitters bind to other receptors of cells and cause changes in receptor cells. Norepinephrine is a neurotransmitter used by the sympathetic nervous system, part of the unwanted nervous system. Neuron The sympathetic nervous system is the release of norepinephrine, which binds to beta receptors in other cells. Propranolol inhibits the sympathetic nervous system by blocking beta receptors in the nerves of the sympathetic system. Since stimulation of the sympathetic nervous system is responsible for increasing the amount of the heart, by blocking the actions of these nerves propranolol reduces heart rate and is useful in the treatment of abnormal heart rhythms.

Propranolol also reduces the muscle contraction of the heart and therefore reduces blood pressure. By reducing heart rate and muscle contraction, propranolol reduces the need for oxygen by the heart muscle. Because heart pain (angina Patrice) occurs when oxygen needs muscle more than oxygen supply, propranolol is helpful in reducing heart pain by reducing the demand for oxygen.

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How to use propranolol?

This medicine is taken by mouth, usually 2 to 4 times a day or as your doctor. Take this medicine before you eat (and if you put it 4 times a day). Measure the liquid medicine with a spoon or measuring device. Do not use a spoon because you may not have a proper dose.

Use this medication regularly to benefit more from it. To help you remember, take it every day at the same time. It is important to continue taking this medication even if you feel well.

This medicine is used to help prevent chest pain or migraine. This medicine should not be used to treat chest pain or migraine when it occurs. Use of other medications (for example, nitroglycerin tablets put under the language for chest pain, sumatriptan for migraines) to relieve the sudden attacks directed by your doctor. Consult your doctor or pharmacist for details.

If you take certain medicines to lower cholesterol (bone connective resins such as cholesteamine or cholesterol), take propranolol at least 1 hour or at least 4 hours after taking this medication.

To cure high blood pressure, it may take 1 to 2 weeks to get the full benefits of this medicine.

If your condition worsens (for example, your usual blood pressure rises, chest pain or migraines will occur more often).

Dosage of Propranolol

The dose is based on your medical condition and response to treatment.

The recommended dose for hypertension using short acting formulations is 80-240 mg twice daily. The maximum dose is 640 mg daily.

The usual dose using long acting formulations is 80-160 mg daily.

The recommended dose for chest pain is 80-320 mg daily using short acting formulations and 80-160 mg daily using long acting formulations.

The usual dose for treatment of abnormal heart rhythms is 10-30 mg 3-4 times daily of short acting formulations.

The recommended dose for preventing migraines is 80-240 mg daily.

Side effects of Propranolol

Along with its needed effects, propranolol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking propranolol:

More Common in children

Cough producing mucus

difficulty with breathing

tightness in the chest

Incidence Not Known

Abdominal or stomach pain and tenderness

black, tarry stools

blistering, peeling, or loosening of the skin

blood in the urine

bloody nose

bloody stools

blurred or loss of vision

body aches or pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

confusion about identity, place, and time




cracks in the skin


decreased awareness or responsiveness

decreased urine output



difficulty with swallowing

dilated neck veins

disturbed color perception

dizziness, faintness, or light-headedness when getting up suddenly from a lying or sitting position

double vision

dryness or soreness of the throat



extreme fatigue

fast, pounding, slow, or irregular heartbeat

fever and chills

general feeling of discomfort, illness, or weakness

hair loss

halos around lights


heavier menstrual periods


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another Side Effects are include:


irregular breathing

light-headedness, dizziness, or fainting

loss of heat from the body

mental depression

mimicry of speech or movements

muscle or joint pain




night blindness

noisy breathing

over bright appearance of lights

paleness or cold feeling in the fingertips and toes


peculiar postures or movements, mannerisms, or grimacing

pinpoint red or purple spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

quick to react or overreact emotionally

rapidly changing moods

rectal bleeding

red skin lesions, often with a purple center

red, irritated eyes

red, swollen skin

reddening of the skin, especially around the ears

runny nose

scaly skin

seeing, hearing, or feeling things that are not there

severe sleepiness

short-term memory loss

shortness of breath

skin irritation or rash, including rash that looks like psoriasis

skin rash, hives, or itching

sores, ulcers, or white spots in the mouth or on the lips


swelling of the eyes, face, fingers, feet, or lower legs

swollen glands

tender, swollen glands in the neck

tightness in the chest

tingling or pain in fingers or toes when exposed to cold

tunnel vision

unusual bleeding or bruising

unusual tiredness or weakness

voice changes


weight gain

Propranolol while Pregnancy

This medicine is recommended only for pregnancy, when there is no substitution and its side effects are more than risk.

Beta blockers may decrease the perfusion of the pairs, bradycardia, embryos and the baby, and hypoglycemia.

Propranolol is safely used to treat a variety of conditions during pregnancy, including hypertension and pheochromocytoma in the mother, and maternal and fetal monotherapy. There are a number of disorders associated with the use of propranolol during pregnancy, but many of these may be related to underlying illness. These disorders include some of the symptoms of beta-block, such as bradycardia, hypoglycemia, and respiratory depression. Other disorders that may be due to propranolol include retardation of intrauterine growth, small pairs, polycythemia, thrombocytopenia and hypocalcemia.

AU TGA Category C pregnancy: Medicines that cause or may cause harm to the baby's baby or infant without anomalies due to their pharmacological effects. These effects may be reversible. Along with the texts, you should consult for more details.

United States FDA Pregnancy Category C: Animal reproduction studies have shown adverse effects on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may be the use of medication in pregnancy.

Drugs that may interact with Propranolol

Some of the products that may be related to this drug include: alpha blockers (such as prazosin), aluminum hydroxide, anticholinergics (such as atropine, scopolamine), chlorpromazine, medicines containing liver enzymes that take propranolol from your body (Such as cimetidine, anti-depressant drugs (SSRIs), including fluoxetine / paroxetine / fluvoxamine, HIV protease inhibitors (including ritonavir, rifamycins, including rifabutin), other drugs for the treatment of high blood pressure (such as clonidine, hydrazine, methyldopa) Epinephrine, Fingolimod, Haloperidol, Other Cardiovascular Medicines For example, digoxin, dispirimide, propofenone, quinidine), moneozone, resiturptane, theophylline, tridizine, thyroid hormones (for example, levothyroxine), warfarin.

Some products have ingredients that can increase your heart rate or blood pressure. Tell your pharmacy what products you use and how to use them safely (especially cough and cold foods, dietary supplements or NSAIDs like ibuprofen / naproxen).

This medication may interfere with certain laboratory tests (including glaucoma screening tests, cardiovascular and cardiovascular stress relief using arthrothamine), which may result in spelling mistakes. Make sure your laboratory personnel and all your doctors know that you are using this medication.

Warnings of Propranolol

If you have diabetes, this product may reduce your heart rate / heart rate, which usually affects when your blood glucose is low (hypoglycemia). Other symptoms of low blood sugar, such as dizziness and sweating, do not affect this medication. This product can also make your blood glucose control harder. Check your blood glucose regularly and share your results with your doctor. Tell your doctor if there are signs of high blood sugar such as thirst / urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

This medicine may cause you dizziness. Alcohol or marijuana causes dizziness. Do not drive, use machines, or do anything that you need to be alert to as long as you can safely do it. Limit alcohol drinks. Talk to your doctor if you use marijuana.

To reduce the risk of dizziness and dizziness, get up slowly when rising from sitting or lie.

Liquid forms of this drug may contain alcohol. Possible reactions are recommended if you have alcohol dependence or liver disease. Ask your doctor or pharmacist about using this product safely.

During pregnancy, this medication should only be needed when needed. Infants exposed to this drug during pregnancy may have low birth weight, low blood sugar, or slow breathing / heart rate. Talk with them about the dangers and benefits of the doctor.

This medicine is transmitted to breast milk. Consult your doctor before breast-feeding.


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