Doxazosin: How to use, Side Effects, Dosage

Doxazosin: How to use, Side Effects, Dosage

What is Doxazosin?

Doxazosin is an oral medication used to treat high blood pressure and benign prostatic hyperplasia (BPH, enlarged ovarian gland of the prostate gland). It belongs to a class of drugs called alpha-1 adrenergic blocks. Other drugs in this class are: alfuzosin (urokrerate), terazosin (Hytrin), thomasulosin (Flomax), sialodosin (Rapaflo) and prazosin (Minipress). Doxazosin prevents norepinephrine, which is released by the nerves from binding to alpha-1 receptors on smooth muscle and blood vessels in the prostate and bladder. By blocking the effect of norepinephrine, dexazosin relaxes smooth muscle. Smooth muscle relaxation around the blood vessels makes them big (flexible) and thus reduces blood pressure. Resting smooth muscles in the prostate and bladder improves the flow of urine and reduces the pain and discomfort of BPH.

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How to use Doxazosin?

Before you start taking doxazosin and every time you refill, read the patient's patient information if necessary from your pharmacist. Ask your doctor or pharmacist if you have questions.

Take doxazosin with or without food, as prescribed by your doctor, usually once a day.

Doxazosin may reduce your blood pressure suddenly, which may lead to dizziness or fainting, usually within 2 to 6 hours after taking it. This risk is higher when you start taking doxazosin for the first time, after your doctor has increased your dose or after you start taking the medicine again. At these times, if you have a weakness, avoid situations that may be harmful.

To avoid dizziness or fatigue, first take dose of dozazosin at bedtime unless the other doctor summarizes this. Your doctor starts the drug with a low dose and gradually increases your dose. Each time you increase your dose or if you restart your medication after discontinuation, take your first dose before bedtime, unless otherwise treated. Follow your doctor's instructions carefully.

The dose is based on your medical condition and response to treatment.

Use doxazosin regularly to get the most out of it. To help you remember, put it at a time every day. If you take a dozazosin for twelve days, you may need to take the medicine at a low dose and gradually increase your dose again. Consult your doctor for details.

It is important to continue taking doxazosin even if you feel well. Most people with high blood pressure do not feel sick.

You should see doxazosin within 1 to 2 weeks. If your condition does not improve or worsen (for example, your blood pressure stays or rises, or your BPH symptoms get worse) tell your doctor.

Dosage of Doxazosin

After the initial dose, with each dose of CARDURA, increase your blood pressure at least 6 hours after taking. If the CARDURA certificate is discontinued for several days, treatment should begin with the initial dose regimen.

Benign prostatic hyperplasia

The recommended dose of CARDURA is 1 mg once a day, in the morning or in the evening.

Depending on the symptoms of the patient's eryodynamic symptoms and BPH symptoms, the dose may be given at 2 to 2 mg and then 4 mg and 8 mg once daily for 1 to 2 weeks. The recommended maximum dose for BPH is 8 mg once a day.

It regularly monitors blood pressure in these patients.

Doxazosin Overdose

The experience with CARDURA overdosage is limited. Two teens, each of whom were clearly taking 40 milligrams of CARDURA with diclofenac and acetaminophen, activated gastric larvae with activated charcoal and completely disappeared. A two-year-old child who accidentally took 4 mg CARDURA was treated with stomach larva and remained in the five-hour emergency care unit. A six-month-old child accidentally received a 1 mg tablet of crushed CARDURA pill and reportedly sleepy. A 32-year-old woman with chronic renal failure, epilepsy, and depression deliberately consumed 60 mg CARDURA (blood serum 0.9 μg / ml; normal blood pressure = 0.02 μg / ml); death resulted from seizure due to hypotension. A 39-year-old woman who takes 70 mg CARDURA, alcohol and Dalmane® (fluorazepam), develops blood pressure that responds to fluid therapy.

Doxazosin while Pregnancy

Animal studies did not succeed in proving the adverse effects of growth in pregnant rabbits and rats at plasma concentrations of 10 and 4 times and affecting human AUC per day at a dose of 12 mg per day. Decreased fetal survival was observed in animals at higher doses. There are no controlled data in human pregnancy.

Side effects of Doxazosin

Along with its needed effects, doxazosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking doxazosin:

  • Dizziness or lightheadedness
  • Blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • fainting (sudden)
  • fast and pounding heartbeat
  • irregular heartbeat
  • shortness of breath
  • sweating
  • swelling of feet or lower legs

Doxazosin

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Painful or prolonged erection of the penis (called priapism), although extremely rare, must have immediate medical attention. If painful or prolonged erection occurs, call your doctor or go to an emergency room as soon as possible

  • Abdominal or stomach pain
  • area rash
  • black, tarry stools
  • bleeding gums
  • blood in urine or stools
  • chest pain or discomfort
  • chills
  • clay-colored stools
  • cough
  • dark urine
  • diarrhea
  • difficulty breathing
  • difficult, burning, or painful urination
  • fever
  • general tiredness and weakness
  • headache, sudden and severe
  • inability to speak
  • itching
  • lab results that show problems with liver
  • light-colored stools
  • loss of appetite
  • noisy breathing
  • pain or discomfort in arms, jaw, back or neck
  • pinpoint red or purple spots on skin
  • rash
  • seizures
  • slow or irregular heartbeat
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swollen glands
  • temporary blindness
  • tightness in chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • upper right abdominal pain
  • vomiting
  • vomiting of blood
  • weakness in arm and/or leg on one side of the body, sudden and severe
  • wheezing
  • yellow eyes and skin

Drugs that may interact with Doxazosin

Common medications checked in combination with doxazosin:

  • amlodipine
  • aspirin
  • Aspirin Low Strength (aspirin)
  • bisoprolol
  • Cialis (tadalafil)
  • clonidine
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Flomax (tamsulosin)
  • ibuprofen
  • Lantus (insulin glargine)
  • Lipitor (atorvastatin)
  • losartan
  • Metoprolol Succinate ER (metoprolol)
  • Metoprolol Tartrate (metoprolol)
  • Paracetamol (acetaminophen)
  • Plavix (clopidogrel)
  • Ramipril
  • sildenafil
  • tamsulosin
  • Viagra (sildenafil)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)

Warnings of Doxazosin

Talk to your doctor or pharmacist before taking doxazosin, if you are allergic to it, or to other alpha blockers, such as prazosin or terazosin; or if you have an allergy. This product may contain inactive material that can cause allergic reactions and other problems. Talk to your pharmacist for more information.

Before taking doxazosin, tell your doctor or pharmacist your medical history, especially heart disease (such as congestive heart failure, angina, heart attacks in the last 6 months), liver disease, eye problems (cataracts, glaucoma).

Doxazosin may cause dizziness or drowsiness. Alcohol or marijuana can cause your dizziness or sleepiness. Do not drive, use machines, or do anything that you need to be alert to as long as you can safely do it. Limit alcohol drinks. Talk to your doctor if you use marijuana. Also refer to the "How to use" section.

Before surgery (including eye / black eye surgery), if you have taken doxazosin or you have ever used other medications (including prescription drugs, over-the-counter prescriptions, and herbal products), to a doctor or dentist Tell yourself.

Elderly adults may be more susceptible to side effects, especially vertigo and low blood pressure when sitting up or lie. These side effects can increase the risk of falling.

During pregnancy, doxazosin should only be needed when needed. Talk with them about the dangers and benefits of the doctor.

Doxazosin

Please if you have any questions about Doxazosin, you can ask us by commenting below this text, we'll answer you as soon as possible.

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